(R)-4-((3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid - Names and Identifiers
Name | (3β,5β)-3-Hydroxycholan-24-oic acid
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Synonyms | isoLCA Isolithocholic acid (ILCA) (3β,5β)-3-Hydroxycholan-24-oic acid (3β,5β)-3-Hydroxycholan-24-oic acid (3beta,5beta)-3-Hydroxycholan-24-oic Acid (R)-4-((3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
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CAS | 1534-35-6
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(R)-4-((3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid - Physico-chemical Properties
Molecular Formula | C24H40O3
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Molar Mass | 376.57 |
Density | 1.073±0.06 g/cm3(Predicted) |
Melting Point | 90-95 °C |
Boling Point | 511.0±23.0 °C(Predicted) |
Solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Off-White |
pKa | 4.76±0.10(Predicted) |
Storage Condition | Refrigerator |
(R)-4-((3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid - Introduction
(3β,5β)-3-Hydroxycholan-24-oic acid ((3β,5β)-3-Hydroxycholan-24-oic acid) is a naturally occurring bile acid. Its chemical structure contains three hydroxyl groups and one 24-carboxylic acid function. The molecular formula of this compound is C24H40O3.
(3β,5β)-3-Hydroxycholan-24-oic acid is a white solid with a bitter taste. Its melting point is about 235-240 degrees Celsius. The compound is soluble in ethanol and methylene chloride, slightly soluble in ether and chloroform, and practically insoluble in water.
(3β,5β)-3-Hydroxycholan-24-oic acid is a member of the bile acid family, which plays an important physiological function in vivo. It is involved in the production of bile and the metabolism of bile acids in the intestine, which contributes to the digestion and absorption of fats. In addition, it can also act as a bile acid receptor agonist, involved in the regulation of cholesterol metabolism and cholesterol hormone synthesis.
The synthesis of
(3β,5β)-3-Hydroxycholan-24-oic acid usually involves the oxidation, cyclization and hydroxyl protection of cholic acid. These steps can be achieved by chemical synthesis and enzymatic reactions.
In terms of safety,(3β,5β)-3-Hydroxycholan-24-oic acid is generally considered safe at appropriate concentrations. As a natural substance present in the human body, it rarely shows side effects at regular doses. However, the dosage should be strictly controlled during use to avoid possible adverse reactions. When using or handling the compound, follow appropriate laboratory safety practices to ensure the safety and health of individuals.
Last Update:2024-04-10 22:29:15